Summary
Definition
History and exam
Key diagnostic factors
- hypertension presenting at a young age or resistant to treatment
- diminished lower extremity pulses
- differential upper and lower extremity blood pressure (BP)
Other diagnostic factors
- systolic ejection murmur
- male gender
- genetic syndrome
- claudication
- headache
- systolic ejection click
- other cardiac anomalies
Risk factors
- male gender
- young age
- FHx
- Turner's syndrome
- DiGeorge's syndrome
- hypoplastic left heart syndrome
- Shone's complex
- PHACE syndrome
Diagnostic investigations
Investigations to consider
- computed tomography (CT) angiography
- magnetic resonance angiography
- cardiac catheterisation
Treatment algorithm
Contributors
Authors

Director Heart Failure, Heart Transplantation
Professor of Pediatrics
Division of Pediatric Cardiology
University of California, San Francisco
San Francisco
CA
Disclosures
JG declares that he has no competing interests.
Dr Jeffrey Gossett wishes to gratefully acknowledge Dr Anna Kamp, a previous contributor to this topic. AK declares that she has no competing interests.
Peer reviewers
Clinical Assistant Professor of Pediatrics
University of Michigan
Ann Arbor
MI
Disclosures
RA declares that he has no competing interests.
Consultant Paediatric Cardiologist and Honorary Senior Lecturer
Great Ormond Street Hospital and Institute of Child Health
London
UK
Disclosures
SK declares that he has no competing interests.
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